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SUBCELLULAR LOCATION

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Main location(s)

Plasma membrane, Cytoplasm

Additional location(s)

Nucleus 

Staining summary

Mainly localized to the cytoplasm and plasma membrane. In addition localized to the nucleus.

Reliability (APE)

High

Antibodies in assay

CAB017105, HPA024377
 

Antibody CAB017105

 

Antibody HPA024377

 

         Cell line U-2 OS

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Location(s)

Plasma membrane, Cytoplasm Nucleus, Cytoplasm 

Staining characteristics

Granular  

Staining intensity

Moderate Moderate 

Validation

Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

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Location(s)

Plasma membrane, Cytoplasm Plasma membrane, Cytoplasm 

Staining characteristics

  

Staining intensity

Weak Strong 

Validation

Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line U-2 OS shows positivity in plasma membrane & cytoplasm.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in nucleus & cytoplasm.
 

Summary

Staining of cytoplasm and plasma membrane in U-251 MG and U-2 OS.   Staining of plasma membrane and cytoplasm in U-251 MG. Staining of nucleus and cytoplasm in U-2 OS.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is supported by literature.
 

Dictionary

Cytoplasm
Nucleus
Plasma membrane