SENP3

GENE INFORMATION

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Gene name

SENP3 (HGNC Symbol)

Synonyms

DKFZP586K0919, DKFZp762A152, SMT3IP1, SSP3, Ulp1

Description

SUMO1/sentrin/SMT3 specific peptidase 3 (HGNC Symbol)

Entrez gene summary

The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM, Jun 2009]

Chromosome

17 (Chromosome progress)

Cytoband

p13.1

Chromosome location (bp)

7465192 - 7475287

Ensembl

ENSG00000161956 (version 73.37)

Entrez gene

26168

UniProt

Q9H4L4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H4L4

Antibodypedia

SENP3 antibodies
 

PROTEIN VIEW

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SENP3-005
 
SENP3-006
 
SENP3-007
 
SENP3-201
 
SENP3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SENP3-005 ENSP00000463358
ENST00000580231
J3QL36
Show all »
Show » 237 27.8 No 0
SENP3-006 ENSP00000462461
ENST00000581093
J3KSF5
Show all »
Show » 82 9.9 No 0
SENP3-007 ENSP00000464172
ENST00000582789
J3QRE4
Show all »
Show » 110 13.3 No 0
SENP3-201 ENSP00000314029
ENST00000321337
J3KNH7
Show all »
Show » 573 64.9 No 0
SENP3-202 ENSP00000403712
ENST00000429205
Q9H4L4
Show all »
Show » Show » 574 65 No 0