SYVN1

GENE INFORMATION

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Gene name

SYVN1 (HGNC Symbol)

Synonyms

DER3, HRD1

Description

Synovial apoptosis inhibitor 1, synoviolin (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

11

Cytoband

q13.1

Chromosome location (bp)

64889252 - 64902004

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000162298 (version 75.37)

Entrez gene

102465449

UniProt

Q86TM6 (UniProt - Evidence at protein level)

neXtProt

NX_Q86TM6

Antibodypedia

SYVN1 antibodies
 

PROTEIN VIEW

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SYVN1-001
 
SYVN1-002
 
SYVN1-004
 
SYVN1-005
 
SYVN1-007
 
SYVN1-009
 
SYVN1-011
 
SYVN1-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYVN1-001 ENSP00000366395
ENST00000377190
Q86TM6
Show all »
Show » Show » 617 67.7 Yes 5
SYVN1-002 ENSP00000294256
ENST00000294256
Q86TM6
Show all »
Show » Show » 616 67.6 Yes 5
SYVN1-004 ENSP00000436984
ENST00000526060
Q86TM6
Show all »
Show » Show » 616 67.6 Yes 5
SYVN1-005 ENSP00000431720
ENST00000528487
E9PK19
Show all »
Show » 237 27.6 Yes 4
SYVN1-007 ENSP00000431215
ENST00000531018
E9PMA1
Show all »
Show » Show » 236 27.7 No 4
SYVN1-009 ENSP00000432888
ENST00000527142
E9PN88
Show all »
Show » 149 17.1 Yes 2
SYVN1-011 ENSP00000302035
ENST00000307289
Q86TM6
Show all »
Show » Show » 565 61.7 Yes 5
SYVN1-015 ENSP00000432166
ENST00000532771
Show » 149 17.2 No 2