SYVN1

GENE INFORMATION

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Gene name

SYVN1 (HGNC Symbol)

Synonyms

DER3, HRD1

Description

synovial apoptosis inhibitor 1, synoviolin (HGNC Symbol)

Entrez gene summary

This gene encodes a protein involved in endoplasmic reticulum (ER)-associated degradation. The encoded protein removes unfolded proteins, accumulated during ER stress, by retrograde transport to the cytosol from the ER. This protein also uses the ubiquitin-proteasome system for additional degradation of unfolded proteins. Sequence analysis identified two transcript variants that encode different isoforms. [provided by RefSeq, May 2011]

Chromosome

11 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

64889252 - 64902004

Ensembl

ENSG00000162298 (version 73.37)

Entrez gene

84447

UniProt

Q86TM6 (UniProt - Evidence at protein level)

neXtProt

NX_Q86TM6

Antibodypedia

SYVN1 antibodies
 

PROTEIN VIEW

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SYVN1-001
 
SYVN1-002
 
SYVN1-004
 
SYVN1-005
 
SYVN1-007
 
SYVN1-009
 
SYVN1-011
 
SYVN1-015
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYVN1-001 ENSP00000366395
ENST00000377190
Q86TM6
Show all »
Show » Show » 617 67.7 Yes 5
SYVN1-002 ENSP00000294256
ENST00000294256
Q86TM6
Show all »
Show » Show » 616 67.6 Yes 5
SYVN1-004 ENSP00000436984
ENST00000526060
Q86TM6
Show all »
Show » Show » 616 67.6 Yes 5
SYVN1-005 ENSP00000431720
ENST00000528487
E9PK19
Show all »
Show » 237 27.6 Yes 4
SYVN1-007 ENSP00000431215
ENST00000531018
E9PMA1
Show all »
Show » Show » 236 27.7 No 4
SYVN1-009 ENSP00000432888
ENST00000527142
E9PN88
Show all »
Show » 149 17.1 Yes 2
SYVN1-011 ENSP00000302035
ENST00000307289
Q86TM6
Show all »
Show » Show » 565 61.7 Yes 5
SYVN1-015 ENSP00000432166
ENST00000532771
Show » 149 17.2 No 2