AK4

GENE INFORMATION

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Gene name

AK4 (HGNC Symbol)

Synonyms

AK3, AK3L1

Description

adenylate kinase 4 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the adenylate kinase family of enzymes. The encoded protein is localized to the mitochondrial matrix. Adenylate kinases regulate the adenine and guanine nucleotide compositions within a cell by catalyzing the reversible transfer of phosphate group among these nucleotides. Five isozymes of adenylate kinase have been identified in vertebrates. Expression of these isozymes is tissue-specific and developmentally regulated. A pseudogene for this gene has been located on chromosome 17. Three transcript variants encoding the same protein have been identified for this gene. Sequence alignment suggests that the gene defined by NM_013410, NM_203464, and NM_001005353 is located on chromosome 1. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

p31.3

Chromosome location (bp)

65613232 - 65697828

Ensembl

ENSG00000162433 (version 73.37)

Entrez gene

205

UniProt

P27144 (UniProt - Evidence at protein level)

neXtProt

NX_P27144

Antibodypedia

AK4 antibodies
 

PROTEIN VIEW

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AK4-001
 
AK4-007
 
AK4-201
 
AK4-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AK4-001 ENSP00000322175
ENST00000327299
P27144
Show all »
Show » Show » 223 25.3 Yes 0
AK4-007 ENSP00000448458
ENST00000546702
D3DQ64
Show all »
Show » 171 19.8 No 0
AK4-201 ENSP00000378743
ENST00000395334
P27144
Show all »
Show » Show » 223 25.3 Yes 0
AK4-202 ENSP00000445912
ENST00000545314
P27144
Show all »
Show » Show » 223 25.3 Yes 0