LMX1A

GENE INFORMATION

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Gene name

LMX1A (HGNC Symbol)

Synonyms

LMX1, LMX1.1

Description

LIM homeobox transcription factor 1, alpha (HGNC Symbol)

Entrez gene summary

This gene encodes a homeodomain and LIM-domain containing protein. The encoded protein is a transcription factor that acts as a positive regulator of insulin gene transcription. This gene also plays a role in the development of dopamine producing neurons during embryogenesis. Mutations in this gene are associated with an increased risk of developing Parkinson's disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Chromosome

1

Cytoband

q23.3

Chromosome location (bp)

165171104 - 165325952

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000162761 (version 75.37)

Entrez gene

4009

UniProt

Q8TE12 (UniProt - Evidence at transcript level)

neXtProt

NX_Q8TE12

Antibodypedia

LMX1A antibodies
 

PROTEIN VIEW

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LMX1A-001
 
LMX1A-002
 
LMX1A-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LMX1A-001 ENSP00000340226
ENST00000342310
Q8TE12
Show all »
Show » Show » 382 42.7 No 0
LMX1A-002 ENSP00000294816
ENST00000294816
Q8TE12
Show all »
Show » Show » 382 42.7 No 0
LMX1A-003 ENSP00000356868
ENST00000367893
Q8TE12
Show all »
Show » Show » 382 42.7 No 0