BPNT1

GENE INFORMATION

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Gene name

BPNT1

Synonyms

Description

3'(2'), 5'-bisphosphate nucleotidase 1 (HGNC Symbol)

Entrez gene summary

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q41

Chromosome location (bp)

220230824 - 220263804

Ensembl

ENSG00000162813 (version 73.37)

Entrez gene

10380

UniProt

O95861 (UniProt - Evidence at protein level)

neXtProt

NX_O95861

Antibodypedia

BPNT1 antibodies
 

PROTEIN VIEW

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BPNT1-001
 
BPNT1-005
 
BPNT1-006
 
BPNT1-008
 
BPNT1-009
 
BPNT1-010
 
BPNT1-201
 
BPNT1-202
 
BPNT1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

BPNT1-001 ENSP00000446828
ENST00000469520
O95861
Show all »
Show » Show » 308 33.4 No 0
BPNT1-005 ENSP00000446953
ENST00000463953
F8W1J0
Show all »
Show » 170 18.3 No 0
BPNT1-006 ENSP00000449883
ENST00000498237
F8VVW8
Show all »
Show » 128 14.2 No 0
BPNT1-008 ENSP00000346862
ENST00000354807
A6NF51
Show all »
Show » 291 31.7 No 0
BPNT1-009 ENSP00000448740
ENST00000480959
F8VRY7
Show all »
Show » 116 12.9 No 0
BPNT1-010 ENSP00000446850
ENST00000498791
F8VZG4
Show all »
Show » 136 14.7 No 0
BPNT1-201 ENSP00000318852
ENST00000322067
O95861
Show all »
Show » Show » 308 33.4 No 0
BPNT1-202 ENSP00000410348
ENST00000414869
B4DUS9
Show all »
Show » 272 29.2 No 0
BPNT1-203 ENSP00000444398
ENST00000544404
B4DPS5
Show all »
Show » 253 27.5 No 0