MAPKAPK2

GENE INFORMATION

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Gene name

MAPKAPK2

Synonyms

Description

mitogen-activated protein kinase-activated protein kinase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q32.1

Chromosome location (bp)

206858289 - 206907628

Ensembl

ENSG00000162889 (version 73.37)

Entrez gene

9261

UniProt

P49137 (UniProt - Evidence at protein level)

neXtProt

NX_P49137

Antibodypedia

MAPKAPK2 antibodies
 

PROTEIN VIEW

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MAPKAPK2-001
 
MAPKAPK2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MAPKAPK2-001 ENSP00000356070
ENST00000367103
P49137
Show all »
Show » Show » 400 45.6 No 1
MAPKAPK2-002 ENSP00000294981
ENST00000294981
P49137
Show all »
Show » Show » 370 42.2 No 1