CAPN2

GENE INFORMATION

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Gene name

CAPN2 (HGNC Symbol)

Synonyms

CANPL2, CANPml, mCANP

Description

calpain 2, (m/II) large subunit (HGNC Symbol)

Entrez gene summary

The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Chromosome

1 (Chromosome progress)

Cytoband

q41

Chromosome location (bp)

223889295 - 223963720

Ensembl

ENSG00000162909 (version 73.37)

Entrez gene

824

UniProt

P17655 (UniProt - Evidence at protein level)

neXtProt

NX_P17655

Antibodypedia

CAPN2 antibodies
 

PROTEIN VIEW

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CAPN2-001
 
CAPN2-009
 
CAPN2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CAPN2-001 ENSP00000295006
ENST00000295006
P17655
Show all »
Show » Show » 700 80 No 0
CAPN2-009 ENSP00000399949
ENST00000434648
C9JWY7
Show all »
Show » Show » 131 14.4 No 0
CAPN2-201 ENSP00000413158
ENST00000433674
P17655
Show all »
Show » Show » 622 71.5 No 0