DUSP19

GENE INFORMATION

? »

Gene name

DUSP19 (HGNC Symbol)

Synonyms

DUSP17, SKRP1

Description

dual specificity phosphatase 19 (HGNC Symbol)

Entrez gene summary

Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).[supplied by OMIM, Dec 2009]

Chromosome

2 (Chromosome progress)

Cytoband

q32.1

Chromosome location (bp)

183943287 - 183964733

Ensembl

ENSG00000162999 (version 73.37)

Entrez gene

142679

UniProt

Q8WTR2 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WTR2

Antibodypedia

DUSP19 antibodies
 

PROTEIN VIEW

? »
 
 
 
DUSP19-001
 
DUSP19-002
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DUSP19-001 ENSP00000346160
ENST00000354221
Q8WTR2
Show all »
Show » Show » 217 24.2 No 0
DUSP19-002 ENSP00000343905
ENST00000342619
Q8WTR2
Show all »
Show » Show » 166 18.3 No 0