EN1

GENE INFORMATION

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Gene name

EN1

Synonyms

Description

engrailed homeobox 1 (HGNC Symbol)

Entrez gene summary

Homeobox-containing genes are thought to have a role in controlling development. In Drosophila, the 'engrailed' (en) gene plays an important role during development in segmentation, where it is required for the formation of posterior compartments. Different mutations in the mouse homologs, En1 and En2, produced different developmental defects that frequently are lethal. The human engrailed homologs 1 and 2 encode homeodomain-containing proteins and have been implicated in the control of pattern formation during development of the central nervous system. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q14.2

Chromosome location (bp)

119599747 - 119605254

Ensembl

ENSG00000163064 (version 73.37)

Entrez gene

2019

UniProt

Q05925 (UniProt - Evidence at protein level)

neXtProt

NX_Q05925

Antibodypedia

EN1 antibodies
 

PROTEIN VIEW

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EN1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EN1-001 ENSP00000295206
ENST00000295206
Q05925
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