ALPP

GENE INFORMATION

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Gene name

ALPP

Synonyms

Description

alkaline phosphatase, placental (HGNC Symbol)

Entrez gene summary

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q37.1

Chromosome location (bp)

233243244 - 233247599

Ensembl

ENSG00000163283 (version 73.37)

Entrez gene

250

UniProt

P05187 (UniProt - Evidence at protein level)

neXtProt

NX_P05187

Antibodypedia

ALPP antibodies
 

PROTEIN VIEW

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ALPP-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALPP-001 ENSP00000375881
ENST00000392027
P05187
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