CXCR1

GENE INFORMATION

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Gene name

CXCR1 (HGNC Symbol)

Synonyms

CD181, CDw128a, CKR-1, CMKAR1, IL8RA

Description

chemokine (C-X-C motif) receptor 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q35

Chromosome location (bp)

219027568 - 219031718

Ensembl

ENSG00000163464 (version 73.37)

Entrez gene

3577

UniProt

P25024 (UniProt - Evidence at protein level)

neXtProt

NX_P25024

Antibodypedia

CXCR1 antibodies
 

PROTEIN VIEW

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CXCR1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CXCR1-001 ENSP00000295683
ENST00000295683
P25024
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