SUCLG1

CANCER ATLAS

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Gene description

Succinate-CoA ligase, alpha subunit

Protein class

Citric acid cycle related proteins, Disease related genes, Enzymes, Mitochondrial proteins, Plasma proteins, Potential drug targets, Predicted secreted proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

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HPA036683
 
 
HPA036684
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Most cancer tissues showed moderate to strong granular cytoplasmic positivity. Pancreatic, urothelial, stomach cancers, Melanomas and lymphomas displayed additional nuclear staining. Few testicular, renal, endometrial and lung cancers were negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected