CDS1

GENE INFORMATION

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Gene name

CDS1

Synonyms

Description

CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1 (HGNC Symbol)

Entrez gene summary

Breakdown products of phosphoinositides are ubiquitous second messengers that function downstream of many G protein-coupled receptors and tyrosine kinases regulating cell growth, calcium metabolism, and protein kinase C activity. This gene encodes an enzyme which regulates the amount of phosphatidylinositol available for signaling by catalyzing the conversion of phosphatidic acid to CDP-diacylglycerol. This enzyme is an integral membrane protein localized to two subcellular domains, the matrix side of the inner mitochondrial membrane where it is thought to be involved in the synthesis of phosphatidylglycerol and cardiolipin and the cytoplasmic side of the endoplasmic reticulum where it functions in phosphatidylinositol biosynthesis. Two genes encoding this enzyme have been identified in humans, one mapping to human chromosome 4q21 and a second to 20p13. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q21.23

Chromosome location (bp)

85504132 - 85572491

Ensembl

ENSG00000163624 (version 73.37)

Entrez gene

1040

UniProt

Q92903 (UniProt - Evidence at transcript level)

neXtProt

NX_Q92903

Antibodypedia

CDS1 antibodies
 

PROTEIN VIEW

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CDS1-001
 
CDS1-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDS1-001 ENSP00000295887
ENST00000295887
Q92903
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Show » Show » 461 53.3 No 9
CDS1-002 ENSP00000421316
ENST00000511298
D6RGC8
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81 8.9 No 0