IL17RC

GENE INFORMATION

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Gene name

IL17RC (HGNC Symbol)

Synonyms

IL17-RL

Description

interleukin 17 receptor C (HGNC Symbol)

Entrez gene summary

This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). Unlike IL-17RA, which is predominantly expressed in hemopoietic cells, and binds with high affinity to only IL-17A, this protein is expressed in nonhemopoietic tissues, and binds both IL-17A and IL-17F with similar affinities. The proinflammatory cytokines, IL-17A and IL-17F, have been implicated in the progression of inflammatory and autoimmune diseases. Multiple alternatively spliced transcript variants encoding different isoforms have been detected for this gene, and it has been proposed that soluble, secreted proteins lacking transmembrane and intracellular domains may function as extracellular antagonists to cytokine signaling. [provided by RefSeq, Feb 2011]

Chromosome

3 (Chromosome progress)

Cytoband

p25.3

Chromosome location (bp)

9958758 - 9975314

Ensembl

ENSG00000163702 (version 73.37)

Entrez gene

84818

UniProt

Q8NAC3 (UniProt - Evidence at protein level)

neXtProt

NX_Q8NAC3

Antibodypedia

IL17RC antibodies
 

PROTEIN VIEW

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IL17RC-001
 
IL17RC-006
 
IL17RC-008
 
IL17RC-009
 
IL17RC-010
 
IL17RC-011
 
IL17RC-014
 
IL17RC-016
 
IL17RC-017
 
IL17RC-019
 
IL17RC-020
 
IL17RC-021
 
IL17RC-022
 
IL17RC-027
 
IL17RC-028
 
IL17RC-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL17RC-001 ENSP00000295981
ENST00000295981
Q8NAC3
Show all »
Show » Show » 791 86.2 Yes 1
IL17RC-006 ENSP00000412777
ENST00000451271
F8WC09
Show all »
Show » 70 7.8 Yes 0
IL17RC-008 ENSP00000432564
ENST00000476810
G3V177
Show all »
44 4.9 Yes 0
IL17RC-009 ENSP00000394996
ENST00000434756
F8WE27
Show all »
98 10.5 Yes 0
IL17RC-010 ENSP00000414609
ENST00000438091
C9JSZ3
Show all »
330 36.6 Yes 0
IL17RC-011 ENSP00000401128
ENST00000436503
C9K0M1
Show all »
416 46.1 Yes 0
IL17RC-014 ENSP00000373323
ENST00000383812
Q8NAC3
Show all »
Show » Show » 705 76.9 Yes 1
IL17RC-016 ENSP00000387675
ENST00000451165
A8K3Q5
Show all »
Show » 91 10.2 Yes 0
IL17RC-017 ENSP00000399396
ENST00000412901
B4DI24
Show all »
242 26.9 Yes 0
IL17RC-019 ENSP00000384969
ENST00000403601
Q8NAC3
Show all »
Show » Show » 720 78.7 Yes 1
IL17RC-020 ENSP00000396064
ENST00000413608
Q8NAC3
Show all »
Show » Show » 707 77.2 Yes 1
IL17RC-021 ENSP00000410834
ENST00000451231
F8WB43
Show all »
Show » 123 13 Yes 0
IL17RC-022 ENSP00000407894
ENST00000455057
Q8NAC3
Show all »
Show » Show » 688 75 Yes 1
IL17RC-027 ENSP00000413914
ENST00000440502
F8WEG5
Show all »
99 10.7 Yes 0
IL17RC-028 ENSP00000390080
ENST00000424206
F8WD65
Show all »
156 16.8 Yes 0
IL17RC-201 ENSP00000395315
ENST00000416074
F5H4Z2
Show all »
Show » 546 59.6 No 1