PRKCD

GENE INFORMATION

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Gene name

PRKCD

Synonyms

Description

protein kinase C, delta (HGNC Symbol)

Entrez gene summary

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]

Chromosome

3 (Chromosome progress)

Cytoband

p21.1

Chromosome location (bp)

53190025 - 53226733

Ensembl

ENSG00000163932 (version 73.37)

Entrez gene

5580

UniProt

Q05655 (UniProt - Evidence at protein level)

neXtProt

NX_Q05655

Antibodypedia

PRKCD antibodies
 

PROTEIN VIEW

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PRKCD-001
 
PRKCD-002
 
PRKCD-004
 
PRKCD-005
 
PRKCD-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PRKCD-001 ENSP00000378217
ENST00000394729
Q05655
Show all »
Show » Show » 676 77.5 No 0
PRKCD-002 ENSP00000331602
ENST00000330452
Q05655
Show all »
Show » Show » 676 77.5 No 0
PRKCD-004 ENSP00000419726
ENST00000478843
C9JZU8
Show all »
Show » 77 8.8 No 0
PRKCD-005 ENSP00000418106
ENST00000487897
C9J9P1
Show all »
Show » 125 14.2 No 0
PRKCD-006 ENSP00000419629
ENST00000464818
C9K0E3
Show all »
Show » 223 25.5 No 0