ABCE1

GENE INFORMATION

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Gene name

ABCE1 (HGNC Symbol)

Synonyms

OABP, RLI, RNASEL1, RNASELI, RNS4I

Description

ATP-binding cassette, sub-family E (OABP), member 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

4 (Chromosome progress)

Cytoband

q31.21

Chromosome location (bp)

146019084 - 146050331

Ensembl

ENSG00000164163 (version 73.37)

Entrez gene

6059

UniProt

P61221 (UniProt - Evidence at protein level)

neXtProt

NX_P61221

Antibodypedia

ABCE1 antibodies
 

PROTEIN VIEW

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ABCE1-001
 
ABCE1-004
 
ABCE1-005
 
ABCE1-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABCE1-001 ENSP00000296577
ENST00000296577
P61221
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Show » Show » 599 67.3 No 0
ABCE1-004 ENSP00000421250
ENST00000502586
D6RGF4
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Show » 210 23.4 No 0
ABCE1-005 ENSP00000423415
ENST00000504292
H0Y990
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Show » 147 16.2 No 0
ABCE1-010 ENSP00000422068
ENST00000507193
D6R9I9
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Show » Show » 421 47 No 0