F2RL2

GENERAL INFORMATION

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Gene name

F2RL2

Gene description

Coagulation factor II (thrombin) receptor-like 2

Protein class

G-protein coupled receptors
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enhanced (gallbladder)
GTEx:Tissue enhanced (salivary gland)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

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Data reliability

Pending normal tissue annotation.
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

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Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enhanced (gallbladder)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (salivary gland)

Organ

Expression



GENE INFORMATION

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Gene name

F2RL2 (HGNC Symbol)

Synonyms

PAR3

Description

Coagulation factor II (thrombin) receptor-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]

Chromosome

5

Cytoband

q13.3

Chromosome location (bp)

76615482 - 76623434

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000164220 (version 78.38)

Entrez gene

2151

UniProt

O00254 (UniProt - Evidence at protein level)

neXtProt

NX_O00254

Antibodypedia

F2RL2 antibodies


PROTEIN BROWSER

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ENST00000296641
 
ENST00000504899
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

F2RL2-001 ENSP00000296641
ENST00000296641
O00254
Show all »
Show » Show » 374 42.5 Yes 7
F2RL2-002 ENSP00000426703
ENST00000504899
O00254
Show all »
Show » Show » 352 40.2 No 7