F2RL2

GENE INFORMATION

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Gene name

F2RL2 (HGNC Symbol)

Synonyms

PAR3

Description

coagulation factor II (thrombin) receptor-like 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Feb 2012]

Chromosome

5 (Chromosome progress)

Cytoband

q13.3

Chromosome location (bp)

75911307 - 75919259

Ensembl

ENSG00000164220 (version 73.37)

Entrez gene

2151

UniProt

O00254 (UniProt - Evidence at protein level)

neXtProt

NX_O00254

Antibodypedia

F2RL2 antibodies
 

PROTEIN VIEW

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F2RL2-001
 
F2RL2-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

F2RL2-001 ENSP00000296641
ENST00000296641
O00254
Show all »
Show » Show » 374 42.5 Yes 7
F2RL2-002 ENSP00000426703
ENST00000504899
O00254
Show all »
Show » Show » 352 40.2 No 7