The Human Protein Atlas

GENE INFORMATION

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Gene name	CTSB
Synonyms
Description	cathepsin B (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
Chromosome	8 (Chromosome progress)
Cytoband	p23.1
Chromosome location (bp)	11700033 - 11726957
Ensembl	ENSG00000164733 (version 69.37)
Entrez gene	1508
UniProt	P07858
neXtProt	NX_P07858
Antibodypedia	CTSB antibodies

PROTEIN VIEW

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CTSB-001		CTSB-002		CTSB-003		CTSB-004		CTSB-005		CTSB-006		CTSB-007		CTSB-009		CTSB-011		CTSB-013		CTSB-015		CTSB-016		CTSB-017		CTSB-018		CTSB-019		CTSB-020		CTSB-021		CTSB-023		CTSB-024		CTSB-025		CTSB-027		CTSB-029		CTSB-030		CTSB-032		CTSB-033		CTSB-201		CTSB-202

PROTEIN INFORMATION

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Splice variant	Ensembl	UniProt	Protein class	Gene ontology	Length (aa)	Molecular mass (kDa)	Signal peptide (predicted)
CTSB-001	ENSP00000345672 ENST00000353047	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-002	ENSP00000432244 ENST00000533455	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-003	ENSP00000435105 ENST00000530640	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-004	ENSP00000433215 ENST00000531089	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-005	ENSP00000434217 ENST00000534510	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-006	ENSP00000409917 ENST00000453527	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-007	ENSP00000342070 ENST00000345125	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes
CTSB-009	ENSP00000433379 ENST00000527215	E9PL32 Show all » « Hide E9PL32 [Target identity:100%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:76%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:60%; Query identity:100%] Cathepsin B E9PID0 [Target identity:35%; Query identity:100%] Cathepsin B E9PR00 [Target identity:23%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	91	10.6	Yes
CTSB-011	ENSP00000436456 ENST00000531551	E9PCB3 Show all » « Hide E9PCB3 [Target identity:100%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:91%; Query identity:100%] Cathepsin B E9PR54 [Target identity:89%; Query identity:100%] Cathepsin B E9PS78 [Target identity:83%; Query identity:100%] Cathepsin B E9PL32 [Target identity:82%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:63%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:50%; Query identity:100%] Cathepsin B E9PID0 [Target identity:29%; Query identity:100%] Cathepsin B E9PR00 [Target identity:19%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	110	12.7	Yes
CTSB-013	ENSP00000435886 ENST00000531502	E9PS78 Show all » « Hide E9PS78 [Target identity:100%; Query identity:100%] Cathepsin B E9PL32 [Target identity:98%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:76%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:59%; Query identity:100%] Cathepsin B E9PID0 [Target identity:34%; Query identity:100%] Cathepsin B E9PR00 [Target identity:22%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	92	10.7	Yes
CTSB-015	ENSP00000436159 ENST00000534636	E9PQM1 Show all » « Hide E9PQM1 [Target identity:100%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:97%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:94%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:85%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:81%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:77%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:57%; Query identity:100%] Cathepsin B E9PR54 [Target identity:56%; Query identity:100%] Cathepsin B E9PL32 [Target identity:52%; Query identity:100%] Cathepsin B E9PS78 [Target identity:52%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:40%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:31%; Query identity:100%] Cathepsin B E9PID0 [Target identity:18%; Query identity:100%] Cathepsin B E9PR00 [Target identity:12%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	175	19.5	Yes
CTSB-016	ENSP00000436074 ENST00000524500	E9PR54 Show all » « Hide E9PR54 [Target identity:100%; Query identity:100%] Cathepsin B E9PS78 [Target identity:93%; Query identity:100%] Cathepsin B E9PL32 [Target identity:92%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:71%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:56%; Query identity:100%] Cathepsin B E9PID0 [Target identity:32%; Query identity:100%] Cathepsin B E9PR00 [Target identity:21%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	98	11.4	Yes
CTSB-017	ENSP00000433995 ENST00000533572	E9PSG5 Show all » « Hide E9PSG5 [Target identity:100%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:97%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:87%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:84%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:80%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:59%; Query identity:100%] Cathepsin B E9PR54 [Target identity:57%; Query identity:100%] Cathepsin B E9PS78 [Target identity:54%; Query identity:100%] Cathepsin B E9PL32 [Target identity:53%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:41%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:32%; Query identity:100%] Cathepsin B E9PID0 [Target identity:18%; Query identity:100%] Cathepsin B E9PR00 [Target identity:12%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	170	18.9	Yes
CTSB-018	ENSP00000436122 ENST00000534149	E9PNL5 Show all » « Hide E9PNL5 [Target identity:100%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:95%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:70%; Query identity:100%] Cathepsin B E9PR54 [Target identity:68%; Query identity:100%] Cathepsin B E9PS78 [Target identity:64%; Query identity:100%] Cathepsin B E9PL32 [Target identity:63%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:48%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:38%; Query identity:100%] Cathepsin B E9PID0 [Target identity:22%; Query identity:100%] Cathepsin B E9PR00 [Target identity:14%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	143	16.1	Yes
CTSB-019	ENSP00000435074 ENST00000530296	E9PLY3 Show all » « Hide E9PLY3 [Target identity:100%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:90%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:86%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:82%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:61%; Query identity:100%] Cathepsin B E9PR54 [Target identity:59%; Query identity:100%] Cathepsin B E9PL32 [Target identity:55%; Query identity:100%] Cathepsin B E9PS78 [Target identity:55%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:42%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:33%; Query identity:100%] Cathepsin B E9PID0 [Target identity:19%; Query identity:100%] Cathepsin B E9PR00 [Target identity:12%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	165	18.5	Yes
CTSB-020	ENSP00000436627 ENST00000526195	E9PHZ5 Show all » « Hide E9PHZ5 [Target identity:100%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:95%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:91%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:67%; Query identity:100%] Cathepsin B E9PR54 [Target identity:65%; Query identity:100%] Cathepsin B E9PL32 [Target identity:61%; Query identity:100%] Cathepsin B E9PS78 [Target identity:61%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:46%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:36%; Query identity:100%] Cathepsin B E9PID0 [Target identity:21%; Query identity:100%] Cathepsin B E9PR00 [Target identity:14%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	149	16.6	Yes
CTSB-021	ENSP00000434725 ENST00000527243	E9PNL5 Show all » « Hide E9PNL5 [Target identity:100%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:95%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:70%; Query identity:100%] Cathepsin B E9PR54 [Target identity:68%; Query identity:100%] Cathepsin B E9PS78 [Target identity:64%; Query identity:100%] Cathepsin B E9PL32 [Target identity:63%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:48%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:38%; Query identity:100%] Cathepsin B E9PID0 [Target identity:22%; Query identity:100%] Cathepsin B E9PR00 [Target identity:14%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	143	16.1	Yes
CTSB-023	ENSP00000435260 ENST00000534382	E9PKX0 Show all » « Hide E9PKX0 [Target identity:100%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:78%; Query identity:100%] Cathepsin B E9PID0 [Target identity:45%; Query identity:100%] Cathepsin B E9PR00 [Target identity:30%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	70	8.1	Yes
CTSB-024	ENSP00000432408 ENST00000532392	E9PR00 Show all » « Hide E9PR00 [Target identity:100%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	21	2.4	Yes
CTSB-025	ENSP00000432077 ENST00000524654	E9PID0 Show all » « Hide E9PID0 [Target identity:100%; Query identity:100%] Cathepsin B E9PR00 [Target identity:65%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	32	3.7	Yes
CTSB-027	ENSP00000431518 ENST00000526645	E9PKQ7 Show all » « Hide E9PKQ7 [Target identity:100%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:74%; Query identity:100%] Cathepsin B E9PR54 [Target identity:72%; Query identity:100%] Cathepsin B E9PS78 [Target identity:67%; Query identity:100%] Cathepsin B E9PL32 [Target identity:66%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:51%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:40%; Query identity:100%] Cathepsin B E9PID0 [Target identity:23%; Query identity:100%] Cathepsin B E9PR00 [Target identity:15%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	136	15.4	Yes
CTSB-029	ENSP00000435367 ENST00000530573	E9PKD0 Show all » « Hide E9PKD0 [Target identity:100%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:88%; Query identity:100%] Cathepsin B E9PR54 [Target identity:85%; Query identity:100%] Cathepsin B E9PS78 [Target identity:80%; Query identity:100%] Cathepsin B E9PL32 [Target identity:79%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:61%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:48%; Query identity:100%] Cathepsin B E9PID0 [Target identity:28%; Query identity:100%] Cathepsin B E9PR00 [Target identity:18%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	114	13.2	Yes
CTSB-030	ENSP00000431143 ENST00000532656	E9PKX0 Show all » « Hide E9PKX0 [Target identity:100%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:78%; Query identity:100%] Cathepsin B E9PID0 [Target identity:45%; Query identity:100%] Cathepsin B E9PR00 [Target identity:30%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	70	8.1	Yes
CTSB-032	ENSP00000433929 ENST00000528965	E9PIS1 Show all » « Hide E9PIS1 [Target identity:100%; Query identity:100%] Cathepsin B E9PID0 [Target identity:58%; Query identity:100%] Cathepsin B E9PR00 [Target identity:38%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	55	6.5	Yes
CTSB-033	ENSP00000435650 ENST00000505496	E9PJ67 Show all » « Hide E9PJ67 [Target identity:100%; Query identity:100%] Cathepsin B E9PR54 [Target identity:97%; Query identity:100%] Cathepsin B E9PS78 [Target identity:91%; Query identity:100%] Cathepsin B E9PL32 [Target identity:90%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:69%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:54%; Query identity:100%] Cathepsin B E9PID0 [Target identity:31%; Query identity:100%] Cathepsin B E9PR00 [Target identity:20%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	101	11.8	Yes
CTSB-201	ENSP00000411254 ENST00000415599	E9PCB3 Show all » « Hide E9PCB3 [Target identity:100%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:91%; Query identity:100%] Cathepsin B E9PR54 [Target identity:89%; Query identity:100%] Cathepsin B E9PS78 [Target identity:83%; Query identity:100%] Cathepsin B E9PL32 [Target identity:82%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:63%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:50%; Query identity:100%] Cathepsin B E9PID0 [Target identity:29%; Query identity:100%] Cathepsin B E9PR00 [Target identity:19%; Query identity:100%] Cathepsin B	Show » « Hide Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins	Show » « Hide GO:0004197 [cysteine-type endopeptidase activity] GO:0005615 [extracellular space] GO:0005625 [soluble fraction] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0007519 [skeletal muscle tissue development] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0043434 [response to peptide hormone stimulus] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4]	110	12.7	Yes
CTSB-202	ENSP00000415889 ENST00000434271	P07858 Show all » « Hide P07858 [Direct mapping] Cathepsin B Cathepsin B light chain Cathepsin B heavy chain E9PQM1 [Target identity:51%; Query identity:100%] Cathepsin B E9PSG5 [Target identity:50%; Query identity:100%] Cathepsin B E9PLY3 [Target identity:48%; Query identity:100%] Cathepsin B E9PHZ5 [Target identity:43%; Query identity:100%] Cathepsin B E9PNL5 [Target identity:42%; Query identity:100%] Cathepsin B E9PKQ7 [Target identity:40%; Query identity:100%] Cathepsin B E9PJ67 [Target identity:29%; Query identity:100%] Cathepsin B E9PR54 [Target identity:28%; Query identity:100%] Cathepsin B E9PS78 [Target identity:27%; Query identity:100%] Cathepsin B E9PL32 [Target identity:26%; Query identity:100%] Cathepsin B E9PKX0 [Target identity:20%; Query identity:100%] Cathepsin B E9PIS1 [Target identity:16%; Query identity:100%] Cathepsin B Q8TAC7 [Target identity:10%; Query identity:100%] Cathepsin B E9PID0 [Target identity:9%; Query identity:100%] Cathepsin B E9PR00 [Target identity:6%; Query identity:100%] Cathepsin B	Show » « Hide Peptidases Cysteine-type peptidases Candidate cancer biomarkers Plasma proteins Candidate cardiovascular disease genes Enzymes Hydrolases Potentially secreted proteins Secreted proteins predicted by MDSP SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Mapped to UniProt SWISS-PROT UniProt - Evidence at protein level	Show » « Hide GO:0004175 [endopeptidase activity] GO:0004197 [cysteine-type endopeptidase activity] GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005615 [extracellular space] GO:0005622 [intracellular] GO:0005625 [soluble fraction] GO:0005737 [cytoplasm] GO:0005739 [mitochondrion] GO:0005764 [lysosome] GO:0005901 [caveola] GO:0006508 [proteolysis] GO:0006914 [autophagy] GO:0006950 [response to stress] GO:0007519 [skeletal muscle tissue development] GO:0008233 [peptidase activity] GO:0008234 [cysteine-type peptidase activity] GO:0009611 [response to wounding] GO:0009612 [response to mechanical stimulus] GO:0009749 [response to glucose stimulus] GO:0009897 [external side of plasma membrane] GO:0009986 [cell surface] GO:0014070 [response to organic cyclic compound] GO:0014075 [response to amine stimulus] GO:0016324 [apical plasma membrane] GO:0030984 [kininogen binding] GO:0036021 [endolysosome lumen] GO:0042277 [peptide binding] GO:0042383 [sarcolemma] GO:0042470 [melanosome] GO:0042981 [regulation of apoptotic process] GO:0043434 [response to peptide hormone stimulus] GO:0045087 [innate immune response] GO:0045471 [response to ethanol] GO:0048471 [perinuclear region of cytoplasm] GO:0050790 [regulation of catalytic activity] GO:0051789 [response to protein stimulus] GO:0060548 [negative regulation of cell death] GO:0070670 [response to interleukin-4] GO:0097067 [cellular response to thyroid hormone stimulus]	339	37.8	Yes

The Human Protein Atlas project is funded by the Knut & Alice Wallenberg foundation.