Fields »

SUBCELLULAR LOCATION

? »

Main location(s)

Nuclear membrane

Additional location(s)

Vesicles 

Staining summary

Mainly localized to nuclear membrane but also to vesicles.

Reliability (APE)

High

Antibodies in assay

HPA008346, HPA008461
 

Antibody HPA008346

 

Antibody HPA008461

 

         Cell line A-431

Toggle channels

 
 

Location(s)

Nuclear membrane Nuclear membrane, Vesicles 

Staining characteristics

  

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-2 OS

Toggle channels

 
 

Location(s)

Nuclear membrane Nuclear membrane, Vesicles 

Staining characteristics

  

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Cell line U-251 MG

Toggle channels

 
 

Location(s)

Nuclear membrane Nuclear membrane, Vesicles 

Staining characteristics

  

Staining intensity

Moderate Moderate 

Validation

One/multiple location(s) supported by experimental gene/protein characterization data.
 
Multiple locations partly supported (at least one) by experimental gene/protein characterization data.
 

Comment

  

         Antibody summary


Immunofluorescent staining of human cell line A-431 shows positivity in nuclear membrane.
 

Immunofluorescent staining of human cell line U-2 OS shows positivity in nuclear membrane & vesicles.
 

Summary

Staining of nuclear membrane in all three cell lines.   Staining of nuclear membrane and vesicles in all three cell lines.  

Validation

The subcellular location is supported by literature.
 
The subcellular location is supported by literature.
 

Dictionary

Nuclear membrane
Endosome