The primary data page shows the detailed antibody staining in 76 different cell types for each analyzed antibody. In addition, for each cell type, a knowledge-based annotated protein expression score based on all analyzed antibodies is displayed furthest to the right. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
The tissues and cell types can be ordered by organ, cell type or alphabetically. If ordered by organ, the tissues are presented in groups according to functional features. If ordered by cell type, the cells are presented in groups related to origin.
This score describes the level of antibody staining observed in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is based on the staining intensity and fraction of stained cells. The images and annotations can be accessed by clicking on the tissue name or score bar. More information can be found in Assays & Annotation.
This score describes a knowledge-based best estimate of the protein expression in the annotated cell types as not detected (n), low (l), medium (m) or high (h). It is a result of stringent evaluation of immunohistochemical staining pattern, RNA data from internal and external sources and available protein/gene characterization data. More information can be found in Assays & Annotation.
Summarizing texts describe the staining pattern for each antibody based on staining intensity, fraction of stained cells and subcellular localization. More information can be found in Assays & Annotation.
Strong cytoplasmic positivity was observed in skeletal muscle cells, bone marrow poietic cells as well as subsets of renal tubules and adrenal cortex cells. The thyroid gland, trophoblastic cells, adipocytes and red blood cells were moderately stained. The remaining normal tissues were weakly stained or negative.
Skeletal myocytes and a subset of adipocytes showed strong cytoplasmic positivity. Fraction of cells in thyroid exhibited strong cytoplasmic and nuclear staining. Salivary gland, stomach, epidermal cells and smooth muscle cells showed moderate staining. Remaining normal tissues were negative.
Strong cytoplasmic immunoreactivity was observed in skeletal muscle. Adipocytes showed distinct positivity in both cytoplasm and nucleus. Remaining normal tissues were generally negative.