FASTK

GENE INFORMATION

? »

Gene name

FASTK (HGNC Symbol)

Synonyms

FAST

Description

Fas-activated serine/threonine kinase (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas-mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis-promoting nuclear RNA-binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full-length natures have not yet been determined. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q36.1

Chromosome location (bp)

150773711 - 150777953

Ensembl

ENSG00000164896 (version 73.37)

Entrez gene

10922

UniProt

Q14296 (UniProt - Evidence at protein level)

neXtProt

NX_Q14296

Antibodypedia

FASTK antibodies
 

PROTEIN VIEW

? »
 
 
 
FASTK-004
 
FASTK-005
 
FASTK-006
 
FASTK-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FASTK-004 ENSP00000418516
ENST00000482571
Q14296
Show all »
Show » Show » 522 58.2 No 0
FASTK-005 ENSP00000297532
ENST00000297532
Q14296
Show all »
Show » Show » 549 61.1 No 0
FASTK-006 ENSP00000324817
ENST00000353841
Q14296
Show all »
Show » Show » 408 45.9 No 0
FASTK-201 ENSP00000444498
ENST00000540185
G3V1R6
Show all »
Show » Show » 159 17 No 0