SYK

GENE INFORMATION

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Gene name

SYK

Synonyms

Description

spleen tyrosine kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of non-receptor type Tyr protein kinases. This protein is widely expressed in hematopoietic cells and is involved in coupling activated immunoreceptors to downstream signaling events that mediate diverse cellular responses, including proliferation, differentiation, and phagocytosis. It is thought to be a modulator of epithelial cell growth and a potential tumour suppressor in human breast carcinomas. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Chromosome

9 (Chromosome progress)

Cytoband

q22.2

Chromosome location (bp)

93564069 - 93660831

Ensembl

ENSG00000165025 (version 73.37)

Entrez gene

6850

UniProt

P43405 (UniProt - Evidence at protein level)

neXtProt

NX_P43405

Antibodypedia

SYK antibodies
 

PROTEIN VIEW

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SYK-001
 
SYK-002
 
SYK-003
 
SYK-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SYK-001 ENSP00000364907
ENST00000375754
P43405
Show all »
Show » Show » 635 72.1 No 0
SYK-002 ENSP00000364898
ENST00000375746
P43405
Show all »
Show » Show » 635 72.1 No 0
SYK-003 ENSP00000364899
ENST00000375747
P43405
Show all »
Show » Show » 612 69.5 No 0
SYK-004 ENSP00000364904
ENST00000375751
P43405
Show all »
Show » Show » 612 69.5 No 0