ALDH1A1

GENE INFORMATION

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Gene name

ALDH1A1 (HGNC Symbol)

Synonyms

ALDH1, PUMB1, RALDH1

Description

aldehyde dehydrogenase 1 family, member A1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the aldehyde dehydrogenase family. Aldehyde dehydrogenase is the next enzyme after alcohol dehydrogenase in the major pathway of alcohol metabolism. There are two major aldehyde dehydrogenase isozymes in the liver, cytosolic and mitochondrial, which are encoded by distinct genes, and can be distinguished by their electrophoretic mobility, kinetic properties, and subcellular localization. This gene encodes the cytosolic isozyme. Studies in mice show that through its role in retinol metabolism, this gene may also be involved in the regulation of the metabolic responses to high-fat diet. [provided by RefSeq, Mar 2011]

Chromosome

9 (Chromosome progress)

Cytoband

q21.13

Chromosome location (bp)

75515578 - 75695358

Ensembl

ENSG00000165092 (version 73.37)

Entrez gene

216

UniProt

P00352 (UniProt - Evidence at protein level)

neXtProt

NX_P00352

Antibodypedia

ALDH1A1 antibodies
 

PROTEIN VIEW

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ALDH1A1-001
 
ALDH1A1-002
 
ALDH1A1-005
 
ALDH1A1-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALDH1A1-001 ENSP00000297785
ENST00000297785
P00352
Show all »
Show » Show » 501 54.9 No 0
ALDH1A1-002 ENSP00000401361
ENST00000446946
Q5SYQ7
Show all »
Show » Show » 203 22.7 No 0
ALDH1A1-005 ENSP00000366138
ENST00000376939
Q5SYQ9
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Show » Show » 230 25.3 No 0
ALDH1A1-006 ENSP00000388026
ENST00000419959
Q5SYQ8
Show all »
Show » Show » 238 26.1 No 0