CLDN3

GENE INFORMATION

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Gene name

CLDN3 (HGNC Symbol)

Synonyms

C7orf1, CPE-R2, CPETR2, HRVP1, RVP1

Description

claudin 3 (HGNC Symbol)

Entrez gene summary

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q11.23

Chromosome location (bp)

73183328 - 73184600

Ensembl

ENSG00000165215 (version 73.37)

Entrez gene

1365

UniProt

O15551 (UniProt - Evidence at protein level)

neXtProt

NX_O15551

Antibodypedia

CLDN3 antibodies
 

PROTEIN VIEW

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CLDN3-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CLDN3-001 ENSP00000378577
ENST00000395145
O15551
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