TSHR

GENE INFORMATION

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Gene name

TSHR (HGNC Symbol)

Synonyms

LGR3

Description

thyroid stimulating hormone receptor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a membrane protein and a major controller of thyroid cell metabolism. The encoded protein is a receptor for thyrothropin and thyrostimulin, and its activity is mediated by adenylate cyclase. Defects in this gene are a cause of several types of hyperthyroidism. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]

Chromosome

14 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

81421333 - 81612646

Ensembl

ENSG00000165409 (version 73.37)

Entrez gene

7253

UniProt

P16473 (UniProt - Evidence at protein level)

neXtProt

NX_P16473

Antibodypedia

TSHR antibodies
 

PROTEIN VIEW

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TSHR-001
 
TSHR-003
 
TSHR-004
 
TSHR-005
 
TSHR-008
 
TSHR-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TSHR-001 ENSP00000441235
ENST00000541158
F5GYU5
Show all »
Show » Show » 764 86.8 Yes 7
TSHR-003 ENSP00000340113
ENST00000342443
P16473
Show all »
Show » Show » 253 28.4 Yes 0
TSHR-004 ENSP00000451202
ENST00000554263
Q0VAP8
Show all »
Show » Show » 231 26 Yes 0
TSHR-005 ENSP00000450549
ENST00000554435
P16473
Show all »
Show » Show » 274 30.8 Yes 0
TSHR-008 ENSP00000451092
ENST00000555326
G3V381
Show all »
Show » Show » 112 12.6 Yes 0
TSHR-201 ENSP00000298171
ENST00000298171
F5GYU5
Show all »
Show » Show » 764 86.8 Yes 7