INPPL1

GENE INFORMATION

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Gene name

INPPL1 (HGNC Symbol)

Synonyms

SHIP2

Description

inositol polyphosphate phosphatase-like 1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009]

Chromosome

11 (Chromosome progress)

Cytoband

q13.4

Chromosome location (bp)

71934745 - 71950149

Ensembl

ENSG00000165458 (version 73.37)

Entrez gene

3636

UniProt

O15357 (UniProt - Evidence at protein level)

neXtProt

NX_O15357

Antibodypedia

INPPL1 antibodies
 

PROTEIN VIEW

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INPPL1-001
 
INPPL1-002
 
INPPL1-005
 
INPPL1-006
 
INPPL1-013
 
INPPL1-014
 
INPPL1-015
 
INPPL1-016
 
INPPL1-017
 
INPPL1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

INPPL1-001 ENSP00000298229
ENST00000298229
O15357
Show all »
Show » Show » 1258 138.6 No 0
INPPL1-002 ENSP00000444619
ENST00000538751
O15357
Show all »
Show » Show » 1016 113.2 No 0
INPPL1-005 ENSP00000440018
ENST00000540329
F5GY16
Show all »
127 14.6 No 0
INPPL1-006 ENSP00000444630
ENST00000537656
F5H588
Show all »
Show » 34 3.9 No 0
INPPL1-013 ENSP00000441094
ENST00000541752
H0YFZ4
Show all »
Show » 197 20.4 No 0
INPPL1-014 ENSP00000321775
ENST00000320683
Show » Show » 149 16.4 No 0
INPPL1-015 ENSP00000440904
ENST00000540973
F5GYK9
Show all »
Show » 22 2 No 0
INPPL1-016 ENSP00000437852
ENST00000535985
41 4.4 No 0
INPPL1-017 ENSP00000440512
ENST00000543234
18 1.5 No 0
INPPL1-201 ENSP00000446360
ENST00000541756
O15357
Show all »
Show » Show » 1016 113.2 No 0