SLC18A2

GENE INFORMATION

? »

Gene name

SLC18A2 (HGNC Symbol)

Synonyms

SVAT, SVMT, VMAT2

Description

solute carrier family 18 (vesicular monoamine), member 2 (HGNC Symbol)

Entrez gene summary

The vesicular monoamine transporter acts to accumulate cytosolic monoamines into synaptic vesicles, using the proton gradient maintained across the synaptic vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs, including reserpine and tetrabenazine (summary by Peter et al., 1993 [PubMed 7905859]). See also SLC18A1 (MIM 193002).[supplied by OMIM, Jan 2011]

Chromosome

10 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

119000604 - 119038941

Ensembl

ENSG00000165646 (version 73.37)

Entrez gene

6571

UniProt

Q05940 (UniProt - Evidence at protein level)

neXtProt

NX_Q05940

Antibodypedia

SLC18A2 antibodies
 

PROTEIN VIEW

? »
 
 
 
SLC18A2-001
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SLC18A2-001 ENSP00000298472
ENST00000298472
Q05940
Show all »
Show » Show » 514 55.7 No >9