ILK

GENE INFORMATION

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Gene name

ILK

Synonyms

Description

integrin-linked kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a protein with a kinase-like domain and four ankyrin-like repeats. The encoded protein associates at the cell membrane with the cytoplasmic domain of beta integrins, where it regulates integrin-mediated signal transduction. Activity of this protein is important in the epithelial to mesenchymal transition, and over-expression of this gene is implicated in tumor growth and metastasis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

Chromosome

11 (Chromosome progress)

Cytoband

p15.4

Chromosome location (bp)

6624961 - 6632102

Ensembl

ENSG00000166333 (version 73.37)

Entrez gene

3611

UniProt

Q13418 (UniProt - Evidence at protein level)

neXtProt

NX_Q13418

Antibodypedia

ILK antibodies
 

PROTEIN VIEW

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ILK-001
 
ILK-002
 
ILK-003
 
ILK-004
 
ILK-005
 
ILK-006
 
ILK-007
 
ILK-008
 
ILK-009
 
ILK-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ILK-001 ENSP00000299421
ENST00000299421
Q13418
Show all »
Show » Show » 452 51.4 No 0
ILK-002 ENSP00000403487
ENST00000420936
Q13418
Show all »
Show » Show » 452 51.4 No 0
ILK-003 ENSP00000379975
ENST00000396751
Q13418
Show all »
Show » Show » 452 51.4 No 0
ILK-004 ENSP00000432796
ENST00000527327
E9PNR4
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Show » 219 24.4 No 0
ILK-005 ENSP00000435323
ENST00000528995
B7Z418
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Show » 391 44.3 No 0
ILK-006 ENSP00000434492
ENST00000532063
E9PQ27
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40 4.6 No 0
ILK-007 ENSP00000433129
ENST00000527394
E9PM54
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Show » 209 23.1 No 0
ILK-008 ENSP00000436062
ENST00000527121
E9PQ52
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36 4.1 No 0
ILK-009 ENSP00000432617
ENST00000526114
E9PQ52
Show all »
36 4.1 No 0
ILK-201 ENSP00000439606
ENST00000537806
B7Z1I0
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Show » 318 36.5 No 0