IDH3A

GENE INFORMATION

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Gene name

IDH3A

Synonyms

Description

isocitrate dehydrogenase 3 (NAD+) alpha (HGNC Symbol)

Entrez gene summary

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the alpha subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q25.1

Chromosome location (bp)

78423840 - 78464291

Ensembl

ENSG00000166411 (version 73.37)

Entrez gene

3419

UniProt

P50213 (UniProt - Evidence at protein level)

neXtProt

NX_P50213

Antibodypedia

IDH3A antibodies
 

PROTEIN VIEW

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 « 
 
IDH3A-001
 
IDH3A-005
 
IDH3A-006
 
IDH3A-008
 
IDH3A-009
 
IDH3A-010
 
IDH3A-011
 
IDH3A-012
 
IDH3A-014
 
IDH3A-015
 
IDH3A-016
 
IDH3A-017
 
IDH3A-018
 
IDH3A-020
 
IDH3A-021
 
IDH3A-022
 
IDH3A-023
 
IDH3A-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IDH3A-001 ENSP00000299518
ENST00000299518
P50213
Show all »
Show » Show » 366 39.6 No 0
IDH3A-005 ENSP00000453033
ENST00000560667
Q68D72
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37 4 No 0
IDH3A-006 ENSP00000453084
ENST00000558554
H0YL72
Show all »
Show » 331 35.8 No 0
IDH3A-008 ENSP00000452620
ENST00000558933
H0YNF8
Show all »
Show » 60 6.2 No 0
IDH3A-009 ENSP00000453992
ENST00000558509
H0YNF8
Show all »
Show » 60 6.2 No 0
IDH3A-010 ENSP00000453438
ENST00000559865
Q68D72
Show all »
37 4 No 0
IDH3A-011 ENSP00000453008
ENST00000559106
36 3.8 No 0
IDH3A-012 ENSP00000452754
ENST00000559186
H0YKD0
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Show » 109 12.1 No 0
IDH3A-014 ENSP00000453222
ENST00000559881
H0YLI6
Show all »
Show » 134 14.8 No 0
IDH3A-015 ENSP00000453903
ENST00000560770
8 0.9 No 0
IDH3A-016 ENSP00000453480
ENST00000557826
H0YM64
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Show » 46 5.2 No 0
IDH3A-017 ENSP00000453989
ENST00000559205
H0YNF5
Show all »
Show » 87 9.3 No 0
IDH3A-018 ENSP00000453795
ENST00000561366
H0YMY5
Show all »
Show » 45 5.2 No 0
IDH3A-020 ENSP00000453459
ENST00000557960
Show » 48 5.2 No 0
IDH3A-021 ENSP00000453338
ENST00000559803
H0YNF8
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Show » 60 6.2 No 0
IDH3A-022 ENSP00000453747
ENST00000561279
H0YMU3
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Show » 175 19.2 No 0
IDH3A-023 ENSP00000453192
ENST00000560396
H0YLF8
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42 4.6 No 0
IDH3A-201 ENSP00000387506
ENST00000441490
B7Z9J8
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Show » 257 28.1 No 0