A2ML1

GENE INFORMATION

? »

Gene name

A2ML1 (HGNC Symbol)

Synonyms

CPAMD9, FLJ25179

Description

alpha-2-macroglobulin-like 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the alpha-macroglobulin superfamily. The encoded protein acts as an inhibitor for several proteases, and has been reported as the p170 antigen recognized by autoantibodies in the autoimmune disease paraneoplastic pemphigus (PNP; PMID: 20805888). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2012]

Chromosome

12 (Chromosome progress)

Cytoband

p13.31

Chromosome location (bp)

8975068 - 9039597

Ensembl

ENSG00000166535 (version 73.37)

Entrez gene

144568

UniProt

A8K2U0 (UniProt - Evidence at protein level)

neXtProt

NX_A8K2U0

Antibodypedia

A2ML1 antibodies
 

PROTEIN VIEW

? »
 
 
 
A2ML1-001
 
A2ML1-003
 
A2ML1-004
 
A2ML1-006
 
A2ML1-008
 
A2ML1-009
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

A2ML1-001 ENSP00000299698
ENST00000299698
A8K2U0
Show all »
Show » Show » 1454 161.1 Yes 0
A2ML1-003 ENSP00000443174
ENST00000541459
H0YGG5
Show all »
Show » Show » 1004 110.6 No 0
A2ML1-004 ENSP00000438292
ENST00000539547
F5H2Z2
Show all »
Show » Show » 963 106 No 0
A2ML1-006 ENSP00000445674
ENST00000537475
Show » 182 20.3 No 0
A2ML1-008 ENSP00000440662
ENST00000536789
F5GYG7
Show all »
81 8.9 No 0
A2ML1-009 ENSP00000440057
ENST00000545692
F5GXP1
Show all »
183 20.2 No 0