HSP90B1

GENE INFORMATION

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Gene name

HSP90B1 (HGNC Symbol)

Synonyms

GP96, GRP94, TRA1

Description

heat shock protein 90kDa beta (Grp94), member 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of a family of adenosine triphosphate(ATP)-metabolizing molecular chaperones with roles in stabilizing and folding other proteins. The encoded protein is localized to melanosomes and the endoplasmic reticulum. Expression of this protein is associated with a variety of pathogenic states, including tumor formation. There is a microRNA gene located within the 5' exon of this gene. There are pseudogenes for this gene on chromosomes 1 and 15. [provided by RefSeq, Aug 2012]

Chromosome

12 (Chromosome progress)

Cytoband

q23.3

Chromosome location (bp)

104323885 - 104347423

Ensembl

ENSG00000166598 (version 73.37)

Entrez gene

7184

UniProt

P14625 (UniProt - Evidence at protein level)

neXtProt

NX_P14625

Antibodypedia

HSP90B1 antibodies
 

PROTEIN VIEW

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HSP90B1-001
 
HSP90B1-006
 
HSP90B1-008
 
HSP90B1-012
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HSP90B1-001 ENSP00000299767
ENST00000299767
P14625
Show all »
Show » Show » 803 92.5 Yes 0
HSP90B1-006 ENSP00000446748
ENST00000549334
F8W026
Show all »
Show » 49 5.6 No 0
HSP90B1-008 ENSP00000446266
ENST00000540297
F8VPC7
Show all »
53 5.9 Yes 0
HSP90B1-012 ENSP00000450215
ENST00000550595
Show » 147 16.9 No 0