PDIA3

GENE INFORMATION

? »

Gene name

PDIA3 (HGNC Symbol)

Synonyms

ERp57, ERp60, ERp61, GRP57, GRP58, HsT17083, P58, PI-PLC

Description

protein disulfide isomerase family A, member 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq, Jul 2008]

Chromosome

15 (Chromosome progress)

Cytoband

q15.3

Chromosome location (bp)

44038590 - 44065477

Ensembl

ENSG00000167004 (version 73.37)

Entrez gene

2923

UniProt

P30101 (UniProt - Evidence at protein level)

neXtProt

NX_P30101

Antibodypedia

PDIA3 antibodies
 

PROTEIN VIEW

? »
 
 
 
PDIA3-001
 
PDIA3-002
 
PDIA3-004
 
PDIA3-006
 
PDIA3-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PDIA3-001 ENSP00000300289
ENST00000300289
P30101
Show all »
Show » Show » 505 56.8 Yes 0
PDIA3-002 ENSP00000391111
ENST00000446523
F8WBW5
Show all »
Show » 75 8.3 Yes 0
PDIA3-004 ENSP00000398005
ENST00000434494
F8WBS6
Show all »
Show » 71 7.6 Yes 0
PDIA3-006 ENSP00000389906
ENST00000455250
H7BZJ3
Show all »
Show » 123 13.5 No 0
PDIA3-201 ENSP00000438260
ENST00000538521
G5EA52
Show all »
Show » 485 55 No 0