IGF2

GENE INFORMATION

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Gene name

IGF2 (HGNC Symbol)

Synonyms

C11orf43, FLJ44734

Description

insulin-like growth factor 2 (somatomedin A) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]

Chromosome

11 (Chromosome progress)

Cytoband

p15.5

Chromosome location (bp)

2150342 - 2170833

Ensembl

ENSG00000167244 (version 73.37)

Entrez gene

3481

UniProt

P01344 (UniProt - Evidence at protein level)

neXtProt

NX_P01344

Antibodypedia

IGF2 antibodies
 

PROTEIN VIEW

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IGF2-001
 
IGF2-002
 
IGF2-003
 
IGF2-004
 
IGF2-005
 
IGF2-007
 
IGF2-009
 
IGF2-014
 
IGF2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGF2-001 ENSP00000414497
ENST00000416167
P01344
Show all »
Show » Show » 180 20.1 Yes 0
IGF2-002 ENSP00000370813
ENST00000381406
P01344
Show all »
Show » Show » 183 20.5 Yes 0
IGF2-003 ENSP00000370802
ENST00000381395
P01344
Show all »
Show » Show » 180 20.1 Yes 0
IGF2-004 ENSP00000370799
ENST00000381392
P01344
Show all »
Show » Show » 183 20.5 Yes 0
IGF2-005 ENSP00000402047
ENST00000418738
P01344
Show all »
Show » Show » 180 20.1 Yes 0
IGF2-007 ENSP00000391826
ENST00000434045
E3UN46
Show all »
Show » Show » 236 26.3 No 1
IGF2-009 ENSP00000370796
ENST00000381389
P01344
Show all »
Show » Show » 180 20.1 Yes 0
IGF2-014 ENSP00000338297
ENST00000337883
P01344
Show all »
Show » Show » 180 20.1 Yes 0
IGF2-201 ENSP00000300632
ENST00000300632
P01344
Show all »
Show » Show » 180 20.1 Yes 0