CA4

GENE INFORMATION

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Gene name

CA4 (HGNC Symbol)

Synonyms

CAIV, Car4, RP17

Description

carbonic anhydrase IV (HGNC Symbol)

Entrez gene summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq, Jul 2008]

Chromosome

17 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

58227297 - 58248260

Ensembl

ENSG00000167434 (version 73.37)

Entrez gene

762

UniProt

P22748 (UniProt - Evidence at protein level)

neXtProt

NX_P22748

Antibodypedia

CA4 antibodies
 

PROTEIN VIEW

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CA4-001
 
CA4-002
 
CA4-003
 
CA4-005
 
CA4-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA4-001 ENSP00000300900
ENST00000300900
P22748
Show all »
Show » Show » 312 35 Yes 1
CA4-002 ENSP00000467465
ENST00000586876
B4DQA4
Show all »
Show » 106 11.6 Yes 0
CA4-003 ENSP00000466964
ENST00000591725
K7ENI8
Show all »
Show » 38 4.2 No 0
CA4-005 ENSP00000465837
ENST00000590203
K7EKY5
Show all »
Show » Show » 184 20.7 No 1
CA4-006 ENSP00000464757
ENST00000587265
99 11.4 No 0