HDGFRP2

GENERAL INFORMATION

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Gene name

HDGFRP2

Gene description

Hepatoma-derived growth factor-related protein 2

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

8
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Ubiquitous nuclear expression.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Supportive based on 2 antibodies.
HPA042559 , HPA044208
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

HDGFRP2

Synonyms

Description

Hepatoma-derived growth factor-related protein 2 (UniProtKB/Swiss-Prot)

Entrez gene summary

This gene encodes a member of the hepatoma-derived growth factor (HDGF) family. The protein includes an N-terminal PWWP domain that binds to methyl-lysine-containing histones, with specific binding of this protein to tri-methylated lysines 36 and 79 of histone H3, and di- and tri-methylated lysine 20 of histone H4. The protein functions in LEDGF/p75-independent HIV-1 replication by determining HIV-1 integration site selection. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

Chromosome

19

Cytoband

p13.3

Chromosome location (bp)

4472287 - 4502211

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000167674 (version 78.38)

Entrez gene

84717

UniProt

Q7Z4V5 (UniProt - Evidence at protein level)

neXtProt

NX_Q7Z4V5

Antibodypedia

HDGFRP2 antibodies


PROTEIN BROWSER

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ENST00000587016
 
ENST00000589486
 
ENST00000592417
 
ENST00000592691
 
ENST00000614903
 
ENST00000616600
 
ENST00000619255
 
ENST00000621835
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HDGFRP2-001 ENSP00000483345
ENST00000616600
Q7Z4V5
Show all »
Show » Show » 671 74.3 No 0
HDGFRP2-002 ENSP00000483702
ENST00000621835
K7EJP7
Show all »
Show » 670 74.2 No 0
HDGFRP2-004 ENSP00000482480
ENST00000614903
Show » 71 7.3 No 0
HDGFRP2-005 ENSP00000467513
ENST00000592417
Show » 153 16.8 No 0
HDGFRP2-007 ENSP00000468175
ENST00000587016
Show » 175 19.8 No 0
HDGFRP2-008 ENSP00000480754
ENST00000619255
Show » 68 7.3 No 0
HDGFRP2-009 ENSP00000467617
ENST00000592691
K7EQ06
Show all »
Show » 24 2.4 No 0
HDGFRP2-010 ENSP00000465267
ENST00000589486
K7EJP7
Show all »
Show » 121 12.7 No 0