KLK2

GENE INFORMATION

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Gene name

KLK2

Synonyms

Description

kallikrein-related peptidase 2 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the grandular kallikrein protein family. Kallikreins are a subgroup of serine proteases that are clustered on chromosome 19. Members of this family are involved in a diverse array of biological functions. The protein encoded by this gene is a highly active trypsin-like serine protease that selectively cleaves at arginine residues. This protein is primarily expressed in prostatic tissue and is responsible for cleaving pro-prostate-specific antigen into its enzymatically active form. This gene is highly expressed in prostate tumor cells and may be a prognostic maker for prostate cancer risk. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Jan 2012]

Chromosome

19 (Chromosome progress)

Cytoband

q13.33

Chromosome location (bp)

51364824 - 51383823

Ensembl

ENSG00000167751 (version 73.37)

Entrez gene

3817

UniProt

P20151 (UniProt - Evidence at transcript level)

neXtProt

NX_P20151

Antibodypedia

KLK2 antibodies
 

PROTEIN VIEW

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 « 
 
KLK2-001
 
KLK2-002
 
KLK2-003
 
KLK2-004
 
KLK2-006
 
KLK2-007
 
KLK2-010
 
KLK2-015
 
KLK2-016
 
KLK2-019
 
KLK2-020
 
KLK2-021
 
KLK2-201
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KLK2-001 ENSP00000313581
ENST00000325321
P20151
Show all »
Show » Show » 261 28.7 Yes 0
KLK2-002 ENSP00000472095
ENST00000594174
M0R1T3
Show all »
Show » Show » 69 7.5 Yes 0
KLK2-003 ENSP00000350748
ENST00000358049
P20151
Show all »
Show » Show » 223 24.7 Yes 0
KLK2-004 ENSP00000471214
ENST00000597439
P20151
Show all »
Show » Show » 164 18.2 Yes 0
KLK2-006 ENSP00000471014
ENST00000597727
Q6T774
Show all »
49 5.1 Yes 0
KLK2-007 ENSP00000472499
ENST00000599121
Q6T774
Show all »
49 5.1 Yes 0
KLK2-010 ENSP00000469770
ENST00000595316
Q6T774
Show all »
49 5.1 Yes 0
KLK2-015 ENSP00000469318
ENST00000600690
M0QXQ7
Show all »
Show » 122 13.1 Yes 0
KLK2-016 ENSP00000472852
ENST00000593493
M0R2W5
Show all »
23 2.7 No 0
KLK2-019 ENSP00000471323
ENST00000599568
M0R0M4
Show all »
Show » 44 4.9 No 0
KLK2-020 ENSP00000471725
ENST00000595050
Show » Show » 184 19.7 No 0
KLK2-021 ENSP00000471321
ENST00000597911
51 5.3 No 0
KLK2-201 ENSP00000375686
ENST00000391810
P20151
Show all »
Show » Show » 159 17.3 No 0