FTH1

GENE INFORMATION

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Gene name

FTH1 (HGNC Symbol)

Synonyms

FHC, FTH, FTHL6, PIG15, PLIF

Description

ferritin, heavy polypeptide 1 (HGNC Symbol)

Entrez gene summary

This gene encodes the heavy subunit of ferritin, the major intracellular iron storage protein in prokaryotes and eukaryotes. It is composed of 24 subunits of the heavy and light ferritin chains. Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues. A major function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in ferritin proteins are associated with several neurodegenerative diseases. This gene has multiple pseudogenes. Several alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q12.3

Chromosome location (bp)

61727190 - 61735132

Ensembl

ENSG00000167996 (version 73.37)

Entrez gene

2495

UniProt

P02794 (UniProt - Evidence at protein level)

neXtProt

NX_P02794

Antibodypedia

FTH1 antibodies
 

PROTEIN VIEW

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FTH1-001
 
FTH1-002
 
FTH1-003
 
FTH1-004
 
FTH1-005
 
FTH1-006
 
FTH1-007
 
FTH1-010
 
FTH1-011
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FTH1-001 ENSP00000273550
ENST00000273550
P02794
Show all »
Show » Show » 183 21.2 No 0
FTH1-002 ENSP00000434403
ENST00000534180
E9PQR3
Show all »
Show » Show » 50 5.6 No 1
FTH1-003 ENSP00000433321
ENST00000526640
G3V192
Show all »
Show » 153 17.7 No 0
FTH1-004 ENSP00000432223
ENST00000532829
E9PRK8
Show all »
Show » 95 11.2 No 0
FTH1-005 ENSP00000431659
ENST00000529191
E9PK45
Show all »
Show » Show » 102 11.6 No 0
FTH1-006 ENSP00000431575
ENST00000529631
E9PKM5
Show all »
Show » 81 9.1 No 0
FTH1-007 ENSP00000433470
ENST00000530019
E9PKY7
Show all »
Show » 114 13.3 No 0
FTH1-010 ENSP00000435111
ENST00000532601
G3V1D1
Show all »
Show » 113 12.9 No 0
FTH1-011 ENSP00000436947
ENST00000529548
E9PPQ4
Show all »
Show » 58 6.7 No 0