PBK

GENE INFORMATION

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Gene name

PBK (HGNC Symbol)

Synonyms

CT84, FLJ14385, Nori-3, SPK, TOPK

Description

PDZ binding kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Chromosome

8 (Chromosome progress)

Cytoband

p21.1

Chromosome location (bp)

27667137 - 27695612

Ensembl

ENSG00000168078 (version 73.37)

Entrez gene

55872

UniProt

Q96KB5 (UniProt - Evidence at protein level)

neXtProt

NX_Q96KB5

Antibodypedia

PBK antibodies
 

PROTEIN VIEW

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PBK-001
 
PBK-002
 
PBK-005
 
PBK-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PBK-001 ENSP00000301905
ENST00000301905
Q96KB5
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Show » Show » 322 36.1 No 0
PBK-002 ENSP00000428489
ENST00000522944
B4DX68
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Show » 333 37.2 No 0
PBK-005 ENSP00000427892
ENST00000521226
E5RFX4
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31 3.5 No 0
PBK-006 ENSP00000428438
ENST00000524266
E5RIE1
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63 7 No 0