KCNJ4

GENE INFORMATION

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Gene name

KCNJ4 (HGNC Symbol)

Synonyms

HIR, hIRK2, HRK1, IRK3, Kir2.3

Description

potassium inwardly-rectifying channel, subfamily J, member 4 (HGNC Symbol)

Entrez gene summary

Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family. The encoded protein has a small unitary conductance compared to other members of this protein family. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

22 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

38822332 - 38851205

Ensembl

ENSG00000168135 (version 73.37)

Entrez gene

3761

UniProt

P48050 (UniProt - Evidence at protein level)

neXtProt

NX_P48050

Antibodypedia

KCNJ4 antibodies
 

PROTEIN VIEW

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KCNJ4-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNJ4-001 ENSP00000306497
ENST00000303592
P48050
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