CX3CR1

GENE INFORMATION

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Gene name

CX3CR1 (HGNC Symbol)

Synonyms

CCRL1, CMKBRL1, CMKDR1, GPR13, V28

Description

chemokine (C-X3-C motif) receptor 1 (HGNC Symbol)

Entrez gene summary

Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

Chromosome

3 (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

39304985 - 39323226

Ensembl

ENSG00000168329 (version 73.37)

Entrez gene

1524

UniProt

P49238 (UniProt - Evidence at protein level)

neXtProt

NX_P49238

Antibodypedia

CX3CR1 antibodies
 

PROTEIN VIEW

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CX3CR1-001
 
CX3CR1-003
 
CX3CR1-004
 
CX3CR1-201
 
CX3CR1-202
 
CX3CR1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CX3CR1-001 ENSP00000382166
ENST00000399220
P49238
Show all »
Show » Show » 355 40.4 No 7
CX3CR1-003 ENSP00000394960
ENST00000435290
C9JN40
Show all »
Show » Show » 166 18.4 No 4
CX3CR1-004 ENSP00000408835
ENST00000412814
C9JLM2
Show all »
Show » Show » 106 11.9 No 2
CX3CR1-201 ENSP00000351059
ENST00000358309
P49238
Show all »
Show » Show » 387 44 No 7
CX3CR1-202 ENSP00000439140
ENST00000541347
P49238
Show all »
Show » Show » 355 40.4 No 7
CX3CR1-203 ENSP00000444928
ENST00000542107
P49238
Show all »
Show » Show » 355 40.4 No 7