ATG4B

GENE INFORMATION

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Gene name

ATG4B (HGNC Symbol)

Synonyms

APG4B, AUTL1, DKFZp586D1822, KIAA0943

Description

autophagy related 4B, cysteine peptidase (HGNC Symbol)

Entrez gene summary

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q37.3

Chromosome location (bp)

242576628 - 242613272

Ensembl

ENSG00000168397 (version 73.37)

Entrez gene

23192

UniProt

Q9Y4P1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y4P1

Antibodypedia

ATG4B antibodies
 

PROTEIN VIEW

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 « 
 
ATG4B-001
 
ATG4B-002
 
ATG4B-005
 
ATG4B-006
 
ATG4B-011
 
ATG4B-015
 
ATG4B-020
 
ATG4B-022
 
ATG4B-023
 
ATG4B-025
 
ATG4B-026
 
ATG4B-027
 
ATG4B-201
 
ATG4B-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATG4B-001 ENSP00000383964
ENST00000405546
Q9Y4P1
Show all »
Show » Show » 380 42.6 No 0
ATG4B-002 ENSP00000384259
ENST00000404914
Q9Y4P1
Show all »
Show » Show » 393 44.3 No 0
ATG4B-005 ENSP00000344960
ENST00000344376
76 8.8 No 0
ATG4B-006 ENSP00000384661
ENST00000402096
Q9Y4P1
Show all »
Show » Show » 331 37 No 0
ATG4B-011 ENSP00000383583
ENST00000400772
F2Z2K8
Show all »
Show » 88 10.2 No 0
ATG4B-015 ENSP00000400050
ENST00000419606
C9J1C1
Show all »
Show » 66 7.7 No 0
ATG4B-020 ENSP00000407389
ENST00000430617
C9JVD5
Show all »
Show » 105 12.1 No 0
ATG4B-022 ENSP00000390597
ENST00000415107
F2Z2K8
Show all »
Show » 88 10.2 No 0
ATG4B-023 ENSP00000409895
ENST00000425239
C9JQ72
Show all »
Show » 266 30.2 No 0
ATG4B-025 ENSP00000383582
ENST00000400771
C9JIK8
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Show » 219 24.8 No 0
ATG4B-026 ENSP00000410526
ENST00000429899
C9J3C0
Show all »
Show » 147 16.6 No 0
ATG4B-027 ENSP00000404783
ENST00000428861
H7C2A6
Show all »
Show » 193 21.2 No 0
ATG4B-201 ENSP00000379692
ENST00000396411
F8WD71
Show all »
Show » 319 35.9 No 0
ATG4B-202 ENSP00000442378
ENST00000474739
F5H7P2
Show all »
Show » Show » 379 42.4 No 0