CHRM1

GENE INFORMATION

? »

Gene name

CHRM1

Synonyms

Description

cholinergic receptor, muscarinic 1 (HGNC Symbol)

Entrez gene summary

The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract. The gene encoding this receptor is localized to 11q13. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q12.3

Chromosome location (bp)

62676151 - 62689279

Ensembl

ENSG00000168539 (version 73.37)

Entrez gene

1128

UniProt

P11229 (UniProt - Evidence at protein level)

neXtProt

NX_P11229

Antibodypedia

CHRM1 antibodies
 

PROTEIN VIEW

? »
 
 
 
CHRM1-001
 
CHRM1-002
 
CHRM1-003
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CHRM1-001 ENSP00000306490
ENST00000306960
P11229
Show all »
Show » Show » 460 51.4 No 7
CHRM1-002 ENSP00000441188
ENST00000543973
Q96RH1
Show all »
Show » Show » 454 50.7 No 7
CHRM1-003 ENSP00000444482
ENST00000536524
F5GZF8
Show all »
Show » Show » 134 14.6 No 3