ADAM18

GENE INFORMATION

? »

Gene name

ADAM18 (HGNC Symbol)

Synonyms

ADAM27, tMDCIII

Description

ADAM metallopeptidase domain 18 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene is a sperm surface protein. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]

Chromosome

8 (Chromosome progress)

Cytoband

p11.22

Chromosome location (bp)

39442008 - 39587583

Ensembl

ENSG00000168619 (version 73.37)

Entrez gene

8749

UniProt

Q9Y3Q7 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9Y3Q7

Antibodypedia

ADAM18 antibodies
 

PROTEIN VIEW

? »
 
 
 
ADAM18-001
 
ADAM18-003
 
ADAM18-004
 
ADAM18-005
 
ADAM18-006
 
ADAM18-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM18-001 ENSP00000265707
ENST00000265707
Q9Y3Q7
Show all »
Show » Show » 739 82.9 Yes 1
ADAM18-003 ENSP00000428083
ENST00000520087
E5RK96
Show all »
Show » 115 13.1 Yes 0
ADAM18-004 ENSP00000429908
ENST00000520772
Q9Y3Q7
Show all »
Show » Show » 182 20.9 Yes 0
ADAM18-005 ENSP00000369195
ENST00000379866
Q9Y3Q7
Show all »
Show » Show » 715 80.2 Yes 1
ADAM18-006 ENSP00000429335
ENST00000520001
E5RIP0
Show all »
62 7.1 Yes 0
ADAM18-201 ENSP00000444729
ENST00000541111
Q0VAI3
Show all »
Show » 153 17.2 No 1