CA7

GENERAL INFORMATION

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Gene name

CA7

Gene description

Carbonic anhydrase VII

Protein class

Enzymes
FDA approved drug targets
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (colon, rectum)
GTEx:Tissue enhanced (colon)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in intestinal tract. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 1 antibody.
HPA047237
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (colon, rectum)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (colon)

Organ

Expression



GENE INFORMATION

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Gene name

CA7

Synonyms

Description

Carbonic anhydrase VII (HGNC Symbol)

Entrez gene summary

Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the salivary glands. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

16

Cytoband

q22.1

Chromosome location (bp)

66844379 - 66854153

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000168748 (version 78.38)

Entrez gene

766

UniProt

P43166 (UniProt - Evidence at protein level)

neXtProt

NX_P43166

Antibodypedia

CA7 antibodies


PROTEIN BROWSER

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ENST00000338437
 
ENST00000394069
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA7-001 ENSP00000345659
ENST00000338437
P43166
Show all »
Show » Show » 264 29.7 No 0
CA7-002 ENSP00000377632
ENST00000394069
P43166
Show all »
Show » Show » 208 23.5 No 0