LETM1

GENE INFORMATION

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Gene name

LETM1

Synonyms

Description

leucine zipper-EF-hand containing transmembrane protein 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19. [provided by RefSeq, Oct 2009]

Chromosome

4 (Chromosome progress)

Cytoband

p16.3

Chromosome location (bp)

1813206 - 1857974

Ensembl

ENSG00000168924 (version 73.37)

Entrez gene

3954

UniProt

O95202 (UniProt - Evidence at protein level)

neXtProt

NX_O95202

Antibodypedia

LETM1 antibodies
 

PROTEIN VIEW

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LETM1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LETM1-001 ENSP00000305653
ENST00000302787
O95202
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