VCX3A

GENERAL INFORMATION

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Gene name

VCX3A

Gene description

Variable charge, X-linked 3A

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

Protein localization

Selective nuclear expression in seminiferus ducts.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining consistent with RNA expression data. Pending external verification. Caution, targets protein from more than one gene.

Data reliability

Supportive based on 2 antibodies.
HPA044996 , HPA049357
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

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Gene name

VCX3A (HGNC Symbol)

Synonyms

VCX-8r, VCX-A, VCX3

Description

Variable charge, X-linked 3A (HGNC Symbol)

Entrez gene summary

This gene belongs to the VCX/Y gene family, which has multiple members on both X and Y chromosomes, and all are expressed exclusively in male germ cells. The X-linked members are clustered on chromosome Xp22 and Y-linked members are two identical copies of the gene within a palindromic region on Yq11. The family members share a high degree of sequence identity, with the exception that a 30-bp unit is tandemly repeated in X-linked members but occurs only once in Y-linked members. The VCX gene cluster is polymorphic in terms of copy number; different individuals may have a different number of VCX genes. VCX/Y genes encode small and highly charged proteins of unknown function. The presence of a putative bipartite nuclear localization signal suggests that VCX/Y members are nuclear proteins. This gene contains 8 repeats of the 30-bp unit. [provided by RefSeq, Jul 2008]

Chromosome

X

Cytoband

p22.31

Chromosome location (bp)

6533618 - 6535118

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000169059 (version 78.38)

Entrez gene

51481

UniProt

Q9NNX9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9NNX9

Antibodypedia

VCX3A antibodies


PROTEIN BROWSER

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ENST00000381089
 
ENST00000398729
 
ENST00000612369
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

VCX3A-001 ENSP00000370479
ENST00000381089
Q9NNX9
Show all »
Show » Show » 186 20 No 0
VCX3A-201 ENSP00000381713
ENST00000398729
E7ESE9
Show all »
Show » 166 17.8 No 0
VCX3A-202 ENSP00000478811
ENST00000612369
Show » 138 14.4 No 0