CA5B

GENE INFORMATION

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Gene name

CA5B

Synonyms

Description

carbonic anhydrase VB, mitochondrial (HGNC Symbol)

Entrez gene summary

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA VB is localized in the mitochondria and shows the highest sequence similarity to the other mitochondrial CA, CA VA. It has a wider tissue distribution than CA VA, which is restricted to the liver. The differences in tissue distribution suggest that the two mitochondrial carbonic anhydrases evolved to assume different physiologic roles. [provided by RefSeq, Jul 2008]

Chromosome

X (Chromosome progress)

Cytoband

p22.2

Chromosome location (bp)

15706953 - 15805747

Ensembl

ENSG00000169239 (version 73.37)

Entrez gene

11238

UniProt

Q9Y2D0 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y2D0

Antibodypedia

CA5B antibodies
 

PROTEIN VIEW

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CA5B-002
 
CA5B-005
 
CA5B-007
 
CA5B-009
 
CA5B-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CA5B-002 ENSP00000417236
ENST00000478341
70 7.7 No 0
CA5B-005 ENSP00000314099
ENST00000318636
Q9Y2D0
Show all »
Show » Show » 317 36.4 No 0
CA5B-007 ENSP00000417553
ENST00000479740
C9JA11
Show all »
Show » 136 15.8 No 0
CA5B-009 ENSP00000418622
ENST00000498004
C9IZP3
Show all »
Show » 76 8.9 No 0
CA5B-201 ENSP00000417021
ENST00000454127
Q9Y2D0
Show all »
Show » Show » 317 36.4 No 0